Scientists prescribed two meals a day rich in fruit, vegetables and fibre.
Only eating breakfast and lunch may be more effective at managing type 2 diabetes than eating smaller, more regular meals, scientists say.
Researchers in Prague fed two groups of 27 people the same calorie diet spread over two or six meals a day.
They found volunteers who ate two meals a day lost more weight than those who ate six, and their blood sugar dropped.
Experts said the study supported “existing evidence” that fewer, larger meals were the way forward.
Type 2 diabetes occurs when the body does not produce enough of the hormone insulin, which controls the amount of sugar in the blood, meaning blood sugar levels become too high.
If untreated, it can lead to heart disease and stroke, nerve damage, light-sensitive eyes and kidney disease.
About 2.9 million people in the UK are affected by diabetes, 90% of whom have the type 2 form of the disease.
Current advice in the UK recommends three meals a day, with healthy snacks.
Scientists at the Institute for Clinical and Experimental Medicine in Prague divided a group of 54 volunteers aged 30 to 70 with type 2 diabetes into two groups of 27 people.
Volunteers were then given either a six-meal-a-day diet (A6) for 12 weeks followed by a two-meal day diet (B2), or vice versa.
The study compared two meals with six meals – as the latter accorded with current practice advice in the Czech Republic, researchers said.
Each diet contained on average 1,700 calories a day.
‘Very Pleasing’ Result
The B2 group ate between 06:00 and 10:00 and then between 12:00 and 16:00, and the A6 group ate their food throughout the day.
Weight loss for the B2 group averaged 1.4kg (3lb) more than A6, and they lost about 4cm (1.5in) more from their waistlines.
Lead scientist Dr Hana Kahleova, at the Institute for Clinical and Experimental Medicine, said the results were “very pleasing”.
She said: “The patients were really afraid they would get hungry in the evening but feelings of hunger were lower as the patients ate until they were satisfied.
“But when they ate six times a day the meals were not leaving them feeling satisfied. It was quite surprising.”