Ecklonia Cava References

  • Ahn G, Amagai Y, Matsuda A, Kang SM, Lee W, Jung K, Oida K, Jang H, Ishizaka S, Matsuda K, Jeon YJ, Jee Y, Matsuda H, Tanaka A. Dieckol, a phlorotannin of Ecklonia cava, suppresses IgE-mediated mast cell activation and passive cutaneous anaphylactic reaction. Exp Dermatol. 2015 Jul 21. doi: 10.1111/exd.12814. [Epub ahead of print] PubMed PMID: 26194398.
  • Ahn G, Amagai Y, Matsuda A, Kang SM, Lee W, Jung K, Oida K, Jang H, Ishizaka S, Matsuda K, Jeon YJ, Jee Y, Matsuda H, Tanaka A. Dieckol, a phlorotannin of Ecklonia cava, suppresses IgE-mediated mast cell activation and passive cutaneous anaphylactic reaction. Exp Dermatol. 2015 Jul . PMID: 26194398.
  • Ahn G, Bing SJ, Kang SM, Lee WW, Lee SH, Matsuda H, Tanaka A, Cho IH, Jeon YJ, Jee Y. The JNk/NFkappaB pathway is required to activate murine lymphocytes induced by a sulfated polysaccharide from Ecklonia cava. Biochim Biophys Acta. 2013 Mar;1830(3):2820-9. PubMed PMID: 23262141.
  • Ahn G, Bing SJ, Kang SM, Lee WW, Lee SH, Matsuda H, Tanaka A, Cho IH, Jeon YJ, Jee Y. The JNk/NFkappaB pathway is required to activate murine lymphocytes induced by a sulfated polysaccharide from Ecklonia cava. Biochim Biophys Acta. 2013 Mar;1830(3) 2820-2829. doi:10.1016/j.bbagen.2012.12.008. PMID: 23262141.
  • Ahn G, Hwang I, Park E, Kim J, Jeon YJ, Lee J, Park JW, Jee Y. Immunomodulatory effects of an enzymatic extract from Ecklonia cava on murine splenocytes. Mar Biotechnol (NY). 2008 May-Jun;10(3):278-89. doi:10.1007/s10126-007-9062-9. Epub 2008 Jan 3. PubMed PMID: 18172723.
  • Ahn G, Hwang I, Park E, Kim J, Jeon YJ, Lee J, Park JW, Jee Y. Immunomodulatory effects of an enzymatic extract from Ecklonia cava on murine splenocytes. Mar Biotechnol (NY). 2008 May-Jun;10(3) 278-289. doi:10.1007/s10126-007-9062-9. PMID: 18172723.
  • Ahn G, Park E, Lee WW, Hyun JW, Lee KW, Shin T, Jeon YJ, Jee Y. Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway. Mar Biotechnol (NY). 2011 Feb;13(1):66-73. doi: 10.1007/s10126-010-9270-6. Epub 2010 May 18. PubMed PMID: 20480199.
  • Ahn G, Park E, Lee WW, Hyun JW, Lee KW, Shin T, Jeon YJ, Jee Y. Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway. Mar Biotechnol (NY). 2011 Feb;13(1) 66-73. doi:10.1007/s10126-010-9270-6. PMID: 20480199.
  • Ahn Gin-Nae, Kim Kil-Nam, Cha Seon-Heui, Song Choon-Bok, Lee Jehee, Heo Moon-Soo, Yeo In-Kyu, Lee Nam-Ho, Jee Young-Heun, Kim Jin-Soo, Heu Min-Soo, Jeon You-Jin. Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H₂O₂-mediated DNA damage Eur Food Res Technol. 2007 Nov;226(1-2) 71-79. doi:10.1007/s00217-006-0510-y. AGR:IND43952846.
  • Ahn JH, Yang YI, Lee KT, Choi JH. Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth. J Cancer Res Clin Oncol. 2015 Feb;141(2):255-68. doi: 10.1007/s00432-014-1819-8. Epub 2014 Sep 13. PubMed PMID: 25216701.
  • Ahn JH, Yang YI, Lee KT, Choi JH. Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth. J Cancer Res Clin Oncol. 2015 Feb;141(2) 255-268. doi:10.1007/s00432-014-1819-8. PMID: 25216701.
  • Ahn MJ, Yoon KD, Min SY, Lee JS, Kim JH, Kim TG, Kim SH, Kim NG, Huh H, Kim J. Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava. Biol Pharm Bull. 2004 Apr;27(4):544-7. PubMed PMID: 15056863.
  • Ahn MJ, Yoon KD, Min SY, Lee JS, Kim JH, Kim TG, Kim SH, Kim NG, Huh H, Kim J. Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava. Biol Pharm Bull. 2004 Apr;27(4) 544-547. doi:10.1248/bpb.27.544. PMID: 15056863.
  • Ale MT, Mikkelsen JD, Meyer AS. Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds. Mar Drugs. 2011;9(10) 2106-2130. doi:10.3390/md9102106. PMID: 22073012; PMCID: PMC3210621.
  • Artan M, Li Y, Karadeniz F, Lee SH, Kim MM, Kim SK. Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava. Bioorg Med Chem. 2008 Sep 1;16(17):7921-6. doi: 10.1016/j.bmc.2008.07.078. Epub 2008 Jul 29. PubMed PMID: 18693022.
  • Artan M, Li Y, Karadeniz F, Lee SH, Kim MM, Kim SK. Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava. Bioorg Med Chem. 2008 Sep;16(17) 7921-7926. doi:10.1016/j.bmc.2008.07.078. PMID: 18693022.
  • Atamna H, Mackey J, Dhahbi JM. Mitochondrial pharmacology: electron transport chain bypass as strategies to treat mitochondrial dysfunction. Biofactors. 2012 Mar-Apr;38(2) 158-166. doi:10.1002/biof.197. PMID: 22419586; PMCID: PMC4299858.
  • Athukorala Y, Kim KN, Jeon YJ. Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food Chem Toxicol. 2006 Jul;44(7):1065-74. Epub 2006 Mar 3. PubMed PMID: 16516367.
  • Athukorala Y, Kim KN, Jeon YJ. Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food Chem Toxicol. 2006 Jul;44(7) 1065-1074. doi:10.1016/j.fct.2006.01.011. PMID: 16516367.
  • Bak SS, Ahn BN, Kim JA, Shin SH, Kim JC, Kim MK, Sung YK, Kim SK. Ecklonia cava promotes hair growth. Clin Exp Dermatol. 2013 Dec;38(8):904-10. doi: 10.1111/ced.12120. PubMed PMID: 24252083.
  • Bak SS, Ahn BN, Kim JA, Shin SH, Kim JC, Kim MK, Sung YK, Kim SK. Ecklonia cava promotes hair growth. Clin Exp Dermatol. 2013 Dec;38(8) 904-910. doi:10.1111/ced.12120. PMID: 24252083.
  • Balboa EM, Moure A, Domínguez H. Valorization of Sargassum muticum Biomass According to the Biorefinery Concept. Mar Drugs. 2015 Jun;13(6) 3745-3760. doi:10.3390/md13063745. PMID: 26110896; PMCID: PMC4483654.
  • Barbosa M, Valentão P, Andrade PB. Bioactive compounds from macroalgae in the new millennium: implications for neurodegenerative diseases. Mar Drugs. 2014 Sep;12(9) 4934-4972. doi:10.3390/md12094934. PMID: 25257784; PMCID: PMC4178484.
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  • Bhatnagar I, Kim SK. Immense essence of excellence: marine microbial bioactive compounds. Mar Drugs. 2010;8(10) 2673-2701. doi:10.3390/md8102673. PMID: 21116414; PMCID: PMC2993000.
  • Bhatnagar I, Kim SK. Marine antitumor drugs: status, shortfalls and strategies. Mar Drugs. 2010;8(10) 2702-2720. doi:10.3390/md8102702. PMID: 21116415; PMCID: PMC2993001.
  • Cao RA, Lee Y, You S. Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava. Int J Biol Macromol. 2014 Jun;67:303-11. doi: 10.1016/j.ijbiomac.2014.03.019. Epub 2014 Mar 21. PubMed PMID: 24661888.
  • Cao RA, Lee Y, You S. Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava. Int J Biol Macromol. 2014 Jun;67 303-311. doi:10.1016/j.ijbiomac.2014.03.019. PMID: 24661888.
  • Cha SH, Ko CI, Kim D, Jeon YJ. Protective effects of phlorotannins against ultraviolet B radiation in zebrafish (Danio rerio). Vet Dermatol. 2012 Feb;23(1):51-6, e12. doi: 10.1111/j.1365-3164.2011.01009.x. Epub 2011 Nov 1. PubMed PMID: 22040269.
  • Cha SH, Ko CI, Kim D, Jeon YJ. Protective effects of phlorotannins against ultraviolet B radiation in zebrafish (Danio rerio). Vet Dermatol. 2012 Feb;23(1) 51-6, e12. doi:10.1111/j.1365-3164.2011.01009.x. PMID: 22040269.
  • Cha SH, Ko SC, Kim D, Jeon YJ. Screening of marine algae for potential tyrosinase inhibitor: those inhibitors reduced tyrosinase activity and melanin synthesis in zebrafish. J Dermatol. 2011 Apr;38(4):354-63. PubMed PMID: 21544943.
  • Cha SH, Ko SC, Kim D, Jeon YJ. Screening of marine algae for potential tyrosinase inhibitor: those inhibitors reduced tyrosinase activity and melanin synthesis in zebrafish. J Dermatol. 2011 Apr;38(4) 354-363. doi:10.1111/j.1346-8138.2010.00983.x. PMID: 21544943.
  • Chan CH, Ngoh GC, Yusoff R. A brief review on anti diabetic plants: Global distribution, active ingredients, extraction techniques and acting mechanisms. Pharmacogn Rev. 2012 Jan;6(11) 22-28. doi:10.4103/0973-7847.95854. PMID: 22654401; PMCID: PMC3358964.
  • Cheng CW, Chang WL, Chang LC, Wu CC, Lin YF, Chen JS. Ferulic Acid, an Angelica sinensis-Derived Polyphenol, Slows the Progression of Membranous Nephropathy in a Mouse Model. Evid Based Complement Alternat Med. 2012;2012 161235. doi:10.1155/2012/161235. PMID: 22844329; PMCID: PMC3403610.
  • Chikaraishi Y, Steffan SA, Ogawa NO, Ishikawa NF, Sasaki Y, Tsuchiya M, Ohkouchi N. High-resolution food webs based on nitrogen isotopic composition of amino acids. Ecol Evol. 2014 Jun;4(12) 2423-2449. doi:10.1002/ece3.1103. PMID: 25360278; PMCID: PMC4203290.
  • Cho S, Han D, Kim SB, Yoon M, Yang H, Jin YH, Jo J, Yong H, Lee SH, Jeon YJ, Shimizu M. Depressive effects on the central nervous system and underlying mechanism of the enzymatic extract and its phlorotannin-rich fraction from Ecklonia cava edible brown seaweed. Biosci Biotechnol Biochem. 2012;76(1):163-8. Epub 2012 Jan 7. PubMed PMID: 22232271.
  • Cho S, Han D, Kim SB, Yoon M, Yang H, Jin YH, Jo J, Yong H, Lee SH, Jeon YJ, Shimizu M. Depressive effects on the central nervous system and underlying mechanism of the enzymatic extract and its phlorotannin-rich fraction from Ecklonia cava edible brown seaweed. Biosci Biotechnol Biochem. 2012;76(1) 163-168. doi:10.1271/bbb.110702. PMID: 22232271.
  • Cho S, Yang H, Jeon YJ, Lee CJ, Jin YH, Baek NI, Kim D, Kang SM, Yoon M, Yong H, Shimizu M, Han D. Phlorotannins of the edible brown seaweed Ecklonia cava Kjellman induce sleep via positive allosteric modulation of gamma-aminobutyric acid type A–benzodiazepine receptor: A novel neurological activity of seaweed polyphenols Food Chem. 2012 Jun;132(3) 1133-1142. doi:10.1016/j.foodchem.2011.08.040. AGR:IND44654477.
  • Choi BW, Lee HS, Shin HC, Lee BH. Multifunctional activity of polyphenolic compounds associated with a potential for Alzheimer’s disease therapy from Ecklonia cava. Phytother Res. 2015 Apr;29(4):549-53. doi: 10.1002/ptr.5282. Epub 2015 Jan 14. PubMed PMID: 25640212.
  • Choi BW, Lee HS, Shin HC, Lee BH. Multifunctional activity of polyphenolic compounds associated with a potential for Alzheimer’s disease therapy from Ecklonia cava. Phytother Res. 2015 Apr;29(4) 549-553. doi:10.1002/ptr.5282. PMID: 25640212.
  • Choi HJ, Park JH, Lee BH, Chee HY, Lee KB, Oh SM. Suppression of NF-κB by dieckol extracted from Ecklonia cava negatively regulates LPS induction of inducible nitric oxide synthase gene. Appl Biochem Biotechnol. 2014 Jun;173(4):957-67. doi: 10.1007/s12010-014-0910-6. Epub 2014 Apr 18. PubMed PMID: 24744158.
  • Choi HJ, Park JH, Lee BH, Chee HY, Lee KB, Oh SM. Suppression of NF-κB by dieckol extracted from Ecklonia cava negatively regulates LPS induction of inducible nitric oxide synthase gene. Appl Biochem Biotechnol. 2014 Jun;173(4) 957-967. doi:10.1007/s12010-014-0910-6. PMID: 24744158.
  • Choi HS, Jeon HJ, Lee OH, Lee BY. Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell-cycle arrest and AMPKα activation. Mol Nutr Food Res. 2015 Aug;59(8):1458-71. doi: 10.1002/mnfr.201500021. Epub 2015 May 28. PubMed PMID: 25944759.
  • Choi HS, Jeon HJ, Lee OH, Lee BY. Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell-cycle arrest and AMPKα activation. Mol Nutr Food Res. 2015 Aug;59(8) 1458-1471. doi:10.1002/mnfr.201500021. PMID: 25944759.
  • Choi JG, Kang OH, Brice OO, Lee YS, Chae HS, Oh YC, Sohn DH, Park H, Choi HG, Kim SG, Shin DW, Kwon DY. Antibacterial activity of Ecklonia cava against methicillin-resistant Staphylococcus aureus and Salmonella spp. Foodborne Pathog Dis. 2010 Apr;7(4):435-41. doi: 10.1089/fpd.2009.0434. PubMed PMID: 20001325.
  • Choi JG, Kang OH, Brice OO, Lee YS, Chae HS, Oh YC, Sohn DH, Park H, Choi HG, Kim SG, Shin DW, Kwon DY. Antibacterial activity of Ecklonia cava against methicillin-resistant Staphylococcus aureus and Salmonella spp. Foodborne Pathog Dis. 2010 Apr;7(4) 435-441. doi:10.1089/fpd.2009.0434. PMID: 20001325.
  • Choi JS, Bae HJ, Kim SJ, Choi IS. In vitro antibacterial and anti-inflammatory properties of seaweed extracts against acne inducing bacteria, Propionibacterium acnes. J Environ Biol. 2011 May;32(3):313-8. PubMed PMID: 22167943.
  • Choi JS, Bae HJ, Kim SJ, Choi IS. In vitro antibacterial and anti-inflammatory properties of seaweed extracts against acne inducing bacteria, Propionibacterium acnes. J Environ Biol. 2011 May;32(3) 313-318. PMID: 22167943.
  • Chowdhury MT, Bangoura I, Kang JY, Cho JY, Joo J, Choi YS, Hwang DS, Hong YK. Comparison of Ecklonia cava, Ecklonia stolonifera and Eisenia bicyclis for phlorotannin extraction. J Environ Biol. 2014 Jul;35(4):713-9. PubMed PMID: 25004758.
  • Chowdhury MT, Bangoura I, Kang JY, Cho JY, Joo J, Choi YS, Hwang DS, Hong YK. Comparison of Ecklonia cava, Ecklonia stolonifera and Eisenia bicyclis for phlorotannin extraction. J Environ Biol. 2014 Jul;35(4) 713-719. PMID: 25004758.
  • Cui Y, Park JY, Wu J, Lee JH, Yang YS, Kang MS, Jung SC, Park JM, Yoo ES, Kim SH, Ahn Jo S, Suk K, Eun SY. Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways. Korean J Physiol Pharmacol. 2015 May;19(3):219-28. doi: 10.4196/kjpp.2015.19.3.219. Epub 2015 Apr 30. PubMed PMID: 25954126; PubMed Central PMCID: PMC4422961.
  • Cui Y, Park JY, Wu J, Lee JH, Yang YS, Kang MS, Jung SC, Park JM, Yoo ES, Kim SH, Ahn Jo S, Suk K, Eun SY. Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways. Korean J Physiol Pharmacol. 2015 May;19(3) 219-228. doi:10.4196/kjpp.2015.19.3.219. PMID: 25954126; PMCID: PMC4422961.
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  • Eo H, Jeon YJ, Lee M, Lim Y. Brown Alga Ecklonia cava polyphenol extract ameliorates hepatic lipogenesis, oxidative stress, and inflammation by activation of AMPK and SIRT1 in high-fat diet-induced obese mice. J Agric Food Chem. 2015 Jan 14;63(1):349-59. PubMed PMID: 25479240.
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  • Ha D, Bing SJ, Cho J, Ahn G, Kim DS, Al-Amin M, Park SJ, Jee Y. Phloroglucinol protects small intestines of mice from ionizing radiation by regulating apoptosis-related molecules: a comparative immunohistochemical study. J Histochem Cytochem. 2013 Jan;61(1) 63-74. doi:10.1369/0022155412468426. PMID: 23117934; PMCID: PMC3534317.
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  • Heo SJ, Ko SC, Cha SH, Kang DH, Park HS, Choi YU, Kim D, Jung WK, Jeon YJ. Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicol In Vitro. 2009 Sep;23(6):1123-30. doi: 10.1016/j.tiv.2009.05.013. Epub 2009 May 31. PubMed PMID: 19490939.
  • Heo SJ, Ko SC, Cha SH, Kang DH, Park HS, Choi YU, Kim D, Jung WK, Jeon YJ. Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicol In Vitro. 2009 Sep;23(6) 1123-1130. doi:10.1016/j.tiv.2009.05.013. PMID: 19490939.
  • Heo SJ, Park PJ, Park EJ, Kim SK, Jeon YJ. Antioxidant activity of enzymatic extracts from a brown seaweed Ecklonia cava by electron spin resonance spectrometry and comet assay. Eur Food Res Technol. 2005 Jul;221(1-2) 41-47. doi:10.1007/s00217-005-1187-3. AGR:IND43790334.
  • Jang J, Ye BR, Heo SJ, Oh C, Kang DH, Kim JH, Affan A, Yoon KT, Choi YU, Park SC, Han S, Qian ZJ, Jung WK, Choi IW. Photo-oxidative stress by ultraviolet-B radiation and antioxidative defense of eckstolonol in human keratinocytes. Environ Toxicol Pharmacol. 2012 Nov;34(3):926-34. doi: 10.1016/j.etap.2012.08.003. Epub 2012 Aug 30. PubMed PMID: 22999063.
  • Jang J, Ye BR, Heo SJ, Oh C, Kang DH, Kim JH, Affan A, Yoon KT, Choi YU, Park SC, Han S, Qian ZJ, Jung WK, Choi IW. Photo-oxidative stress by ultraviolet-B radiation and antioxidative defense of eckstolonol in human keratinocytes. Environ Toxicol Pharmacol. 2012 Nov;34(3) 926-934. doi:10.1016/j.etap.2012.08.003. PMID: 22999063.
  • Joe MJ, Kim SN, Choi HY, Shin WS, Park GM, Kang DW, Kim YK. The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts. Biol Pharm Bull. 2006 Aug;29(8):1735-9. PubMed PMID: 16880634.
  • Joe MJ, Kim SN, Choi HY, Shin WS, Park GM, Kang DW, Kim YK. The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts. Biol Pharm Bull. 2006 Aug;29(8) 1735-1739. doi:10.1248/bpb.29.1735. PMID: 16880634.
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  • Jung HA, Kim JI, Choung SY, Choi JS. Protective effect of the edible brown alga Ecklonia stolonifera on doxorubicin-induced hepatotoxicity in primary rat hepatocytes. J Pharm Pharmacol. 2014 Aug;66(8) 1180-1188. doi:10.1111/jphp.12241. PMID: 24628384.
  • Jung WK, Ahn YW, Lee SH, Choi YH, Kim SK, Yea SS, Choi I, Park SG, Seo SK, Lee SW, Choi IW. Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways. Food Chem Toxicol. 2009 Feb;47(2):410-7. doi: 10.1016/j.fct.2008.11.041. Epub 2008 Dec 11. PubMed PMID: 19111593.
  • Jung WK, Ahn YW, Lee SH, Choi YH, Kim SK, Yea SS, Choi I, Park SG, Seo SK, Lee SW, Choi IW. Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways. Food Chem Toxicol. 2009 Feb;47(2) 410-417. doi:10.1016/j.fct.2008.11.041. PMID: 19111593.
  • Jung WK, Heo SJ, Jeon YJ, Lee CM, Park YM, Byun HG, Choi YH, Park SG, Choi IW. Inhibitory effects and molecular mechanism of dieckol isolated from marine brown alga on COX-2 and iNOS in microglial cells. J Agric Food Chem. 2009 May 27;57(10):4439-46. doi: 10.1021/jf9003913. Epub 2009 May 1. PubMed PMID: 19408937.
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  • Kang C, Jin YB, Lee H, Cha M, Sohn ET, Moon J, Park C, Chun S, Jung ES, Hong JS, Kim SB, Kim JS, Kim E. Brown alga Ecklonia cava attenuates type 1 diabetes by activating AMPK and Akt signaling pathways. Food Chem Toxicol. 2010 Feb;48(2):509-16. doi: 10.1016/j.fct.2009.11.004. Epub 2009 Nov 11. PubMed PMID: 19913068.
  • Kang C, Jin YB, Lee H, Cha M, Sohn ET, Moon J, Park C, Chun S, Jung ES, Hong JS, Kim SB, Kim JS, Kim E. Brown alga Ecklonia cava attenuates type 1 diabetes by activating AMPK and Akt signaling pathways. Food Chem Toxicol. 2010 Feb;48(2) 509-516. doi:10.1016/j.fct.2009.11.004. PMID: 19913068.
  • Kang IJ, Jang BG, In S, Choi B, Kim M, Kim MJ. Phlorotannin-rich Ecklonia cava reduces the production of beta-amyloid by modulating alpha- and gamma-secretase expression and activity. Neurotoxicology. 2013 Jan;34:16-24. doi: 10.1016/j.neuro.2012.09.013. Epub 2012 Oct 4. PubMed PMID: 23041113.
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  • Kang IJ, Jeon YE, Yin XF, Nam JS, You SG, Hong MS, Jang BG, Kim MJ. Butanol extract of Ecklonia cava prevents production and aggregation of beta-amyloid, and reduces beta-amyloid mediated neuronal death. Food Chem Toxicol. 2011 Sep;49(9):2252-9. doi: 10.1016/j.fct.2011.06.023. Epub 2011 Jun 13. PubMed PMID: 21693162.
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  • Kang JI, Kim SC, Kim MK, Boo HJ, Jeon YJ, Koh YS, Yoo ES, Kang SM, Kang HK. Effect of Dieckol, a component of Ecklonia cava, on the promotion of hair growth. Int J Mol Sci. 2012;13(5):6407-23. doi: 10.3390/ijms13056407. Epub 2012 May 23. PubMed PMID: 22754373; PubMed Central PMCID: PMC3382810.
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  • Kang K, Hwang HJ, Hong DH, Park Y, Kim SH, Lee BH, Shin HC. Antioxidant and antiinflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture. Res Commun Mol Pathol Pharmacol. 2004;115-116:77-95. PubMed PMID: 17564307.
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  • Kang KA, Lee KH, Chae S, Koh YS, Yoo BS, Kim JH, Ham YM, Baik JS, Lee NH, Hyun JW. Triphlorethol-A from Ecklonia cava protects V79-4 lung fibroblast against hydrogen peroxide induced cell damage. Free Radic Res. 2005 Aug;39(8):883-92. PubMed PMID: 16036369.
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  • Kang KA, Lee KH, Chae S, Zhang R, Jung MS, Ham YM, Baik JS, Lee NH, Hyun JW. Cytoprotective effect of phloroglucinol on oxidative stress induced cell damage via catalase activation. J Cell Biochem. 2006 Feb 15;97(3):609-20. PubMed PMID: 16215988.
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  • Kang KA, Lee KH, Chae S, Zhang R, Jung MS, Lee Y, Kim SY, Kim HS, Joo HG, Park JW, Ham YM, Lee NH, Hyun JW. Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells. FEBS Lett. 2005 Nov 21;579(28):6295-304. Epub 2005 Oct 19. PubMed PMID: 16253238.
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  • Kang KA, Zhang R, Chae S, Lee SJ, Kim J, Kim J, Jeong J, Lee J, Shin T, Lee NH, Hyun JW. Phloroglucinol (1,3,5-trihydroxybenzene) protects against ionizing radiation-induced cell damage through inhibition of oxidative stress in vitro and in vivo. Chem Biol Interact. 2010 May 14;185(3):215-26. doi: 10.1016/j.cbi.2010.02.031. Epub 2010 Feb 25. PubMed PMID: 20188716.
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  • Kang KA, Zhang R, Lee KH, Chae S, Kim BJ, Kwak YS, Park JW, Lee NH, Hyun JW. Protective effect of triphlorethol-A from Ecklonia cava against ionizing radiation in vitro. J Radiat Res. 2006 Mar;47(1):61-8. PubMed PMID: 16571919.
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  • Kang KA, Zhang R, Piao MJ, Ko DO, Wang ZH, Lee K, Kim BJ, Shin T, Park JW, Lee NH, Yoo BS, Hyun JW. Inhibitory effects of triphlorethol-A on MMP-1 induced by oxidative stress in human keratinocytes via ERK and AP-1 inhibition. J Toxicol Environ Health A. 2008;71(15):992-9. doi: 10.1080/01932690801934653. PubMed PMID: 18569608.
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  • Kang MC, Ahn G, Yang X, Kim KN, Kang SM, Lee SH, Ko SC, Ko JY, Kim D, Kim YT, Jee Y, Park SJ, Jeon YJ. Hepatoprotective effects of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice. Food Chem Toxicol. 2012 Jun;50(6):1986-91. doi: 10.1016/j.fct.2012.03.078. Epub 2012 Apr 4. PubMed PMID: 22504843.
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  • Kang MC, Cha SH, Wijesinghe WA, Kang SM, Lee SH, Kim EA, Song CB, Jeon YJ. Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo. Food Chem. 2013 Jun 1;138(2-3):950-5. doi: 10.1016/j.foodchem.2012.11.005. Epub 2012 Nov 12. PubMed PMID: 23411200.
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  • Kang MC, Kim KN, Kang SM, Yang X, Kim EA, Song CB, Nah JW, Jang MK, Lee JS, Jung WK, Jeon YJ. Protective effect of dieckol isolated from Ecklonia cava against ethanol caused damage in vitro and in zebrafish model. Environ Toxicol Pharmacol. 2013 Nov;36(3):1217-26. doi: 10.1016/j.etap.2013.09.018. Epub 2013 Oct 7. PubMed PMID: 24189014.
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  • Kang MC, Wijesinghe WA, Lee SH, Kang SM, Ko SC, Yang X, Kang N, Jeon BT, Kim J, Lee DH, Jeon YJ. Dieckol isolated from brown seaweed Ecklonia cava attenuates type ІІ diabetes in db/db mouse model. Food Chem Toxicol. 2013 Mar;53:294-8. doi: 10.1016/j.fct.2012.12.012. Epub 2012 Dec 20. PubMed PMID: 23261675.
  • Kang MC, Wijesinghe WA, Lee SH, Kang SM, Ko SC, Yang X, Kang N, Jeon BT, Kim J, Lee DH, Jeon YJ. Dieckol isolated from brown seaweed Ecklonia cava attenuates type ІІ diabetes in db/db mouse model. Food Chem Toxicol. 2013 Mar;53 294-298. doi:10.1016/j.fct.2012.12.012. PMID: 23261675.
  • Kang MH, Kim IH, Nam TJ. Phloroglucinol induces apoptosis via apoptotic signaling pathways in HT-29 colon cancer cells. Oncol Rep. 2014 Oct;32(4) 1341-1346. doi:10.3892/or.2014.3355. PMID: 25070748; PMCID: PMC4148371.
  • Kang NJ, Koo DH, Kang GJ, Han SC, Lee BW, Koh YS, Hyun JW, Lee NH, Ko MH, Kang HK, Yoo ES. Dieckol, a Component of Ecklonia cava, Suppresses the Production of MDC/CCL22 via Down-Regulating STAT1 Pathway in Interferon-γ Stimulated HaCaT Human Keratinocytes. Biomol Ther (Seoul). 2015 May;23(3):238-44. doi: 10.4062/biomolther.2014.141. Epub 2015 May 1. PubMed PMID: 25995822; PubMed Central PMCID: PMC4428716.
  • Kang NJ, Koo DH, Kang GJ, Han SC, Lee BW, Koh YS, Hyun JW, Lee NH, Ko MH, Kang HK, Yoo ES. Dieckol, a Component of Ecklonia cava, Suppresses the Production of MDC/CCL22 via Down-Regulating STAT1 Pathway in Interferon-γ Stimulated HaCaT Human Keratinocytes. Biomol Ther (Seoul). 2015 May;23(3) 238-244. doi:10.4062/biomolther.2014.141. PMID: 25995822; PMCID: PMC4428716.
  • Kang SM, Cha SH, Ko JY, Kang MC, Kim D, Heo SJ, Kim JS, Heu MS, Kim YT, Jung WK, Jeon YJ. Neuroprotective effects of phlorotannins isolated from a brown alga, Ecklonia cava, against H2O2-induced oxidative stress in murine hippocampal HT22 cells. Environ Toxicol Pharmacol. 2012 Jul;34(1):96-105. doi: 10.1016/j.etap.2012.03.006. Epub 2012 Mar 13. PubMed PMID: 22465981.
  • Kang SM, Cha SH, Ko JY, Kang MC, Kim D, Heo SJ, Kim JS, Heu MS, Kim YT, Jung WK, Jeon YJ. Neuroprotective effects of phlorotannins isolated from a brown alga, Ecklonia cava, against H2O2-induced oxidative stress in murine hippocampal HT22 cells. Environ Toxicol Pharmacol. 2012 Jul;34(1) 96-105. doi:10.1016/j.etap.2012.03.006. PMID: 22465981.
  • Kang SM, Heo SJ, Kim KN, Lee SH, Yang HM, Kim AD, Jeon YJ. Molecular docking studies of a phlorotannin, dieckol isolated from Ecklonia cava with tyrosinase inhibitory activity. Bioorg Med Chem. 2012 Jan 1;20(1):311-6. doi: 10.1016/j.bmc.2011.10.078. Epub 2011 Nov 4. PubMed PMID: 22112542.
  • Kang SM, Heo SJ, Kim KN, Lee SH, Yang HM, Kim AD, Jeon YJ. Molecular docking studies of a phlorotannin, dieckol isolated from Ecklonia cava with tyrosinase inhibitory activity. Bioorg Med Chem. 2012 Jan;20(1) 311-316. doi:10.1016/j.bmc.2011.10.078. PMID: 22112542.
  • Kang SM, Lee SH, Heo SJ, Kim KN, Jeon YJ. Evaluation of antioxidant properties of a new compound, pyrogallol-phloroglucinol-6,6′-bieckol isolated from brown algae, Ecklonia cava. Nutr Res Pract. 2011 Dec;5(6):495-502. doi: 10.4162/nrp.2011.5.6.495. Epub 2011 Dec 31. PubMed PMID: 22259673; PubMed Central PMCID: PMC3259291.
  • Kang SM, Lee SH, Heo SJ, Kim KN, Jeon YJ. Evaluation of antioxidant properties of a new compound, pyrogallol-phloroglucinol-6,6′-bieckol isolated from brown algae, Ecklonia cava. Nutr Res Pract. 2011 Dec;5(6) 495-502. doi:10.4162/nrp.2011.5.6.495. PMID: 22259673; PMCID: PMC3259291.
  • Karadeniz F, Kang KH, Park JW, Park SJ, Kim SK. Anti-HIV-1 activity of phlorotannin derivative 8,4‴-dieckol from Korean brown alga Ecklonia cava. Biosci Biotechnol Biochem. 2014;78(7):1151-8. doi: 10.1080/09168451.2014.923282. Epub 2014 Jun 12. PubMed PMID: 25229850.
  • Karadeniz F, Kang KH, Park JW, Park SJ, Kim SK. Anti-HIV-1 activity of phlorotannin derivative 8,4‴-dieckol from Korean brown alga Ecklonia cava. Biosci Biotechnol Biochem. 2014;78(7) 1151-1158. doi:10.1080/09168451.2014.923282. PMID: 25229850.
  • Kawai H, Kitamura A, Mimura M, Mimura T, Tahara T, Aida D, Sato K, Sasaki H. Radioactive cesium accumulation in seaweeds by the Fukushima 1 Nuclear Power Plant accident-two years’ monitoring at Iwaki and its vicinity. J Plant Res. 2014;127(1) 23-42. doi:10.1007/s10265-013-0603-1. PMID: 24310613; PMCID: PMC3882568.
  • Kim AD, Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW, Hyun CL, Kang HK, Lee NH, Hyun JW. Cytoprotective effect of eckol against oxidative stress-induced mitochondrial dysfunction: involvement of the FoxO3a/AMPK pathway. J Cell Biochem. 2014 Aug;115(8):1403-11. doi: 10.1002/jcb.24790. PubMed PMID: 24700636.
  • Kim AD, Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW, Hyun CL, Kang HK, Lee NH, Hyun JW. Cytoprotective effect of eckol against oxidative stress-induced mitochondrial dysfunction: involvement of the FoxO3a/AMPK pathway. J Cell Biochem. 2014 Aug;115(8) 1403-1411. doi:10.1002/jcb.24790. PMID: 24700636.
  • Kim DH, Kim KB, Cho JY, Ahn DH. Inhibitory effects of brown algae extracts on histamine production in mackerel muscle via inhibition of growth and histidine decarboxylase activity of Morganella morganii. J Microbiol Biotechnol. 2014 Apr;24(4):465-74. PubMed PMID: 24394193.
  • Kim DH, Kim KB, Cho JY, Ahn DH. Inhibitory effects of brown algae extracts on histamine production in mackerel muscle via inhibition of growth and histidine decarboxylase activity of Morganella morganii. J Microbiol Biotechnol. 2014 Apr;24(4) 465-474. doi:10.4014/jmb.1309.09071. PMID: 24394193.
  • Kim EA, Lee SH, Ko CI, Cha SH, Kang MC, Kang SM, Ko SC, Lee WW, Ko JY, Lee JH, Kang N, Oh JY, Ahn G, Jee YH, Jeon YJ. Protective effect of fucoidan against AAPH-induced oxidative stress in zebrafish model. Carbohydr Polym. 2014 Feb 15;102:185-91. doi: 10.1016/j.carbpol.2013.11.022. Epub 2013 Nov 27. PubMed PMID: 24507271.
  • Kim EA, Lee SH, Ko CI, Cha SH, Kang MC, Kang SM, Ko SC, Lee WW, Ko JY, Lee JH, Kang N, Oh JY, Ahn G, Jee YH, Jeon YJ. Protective effect of fucoidan against AAPH-induced oxidative stress in zebrafish model. Carbohydr Polym. 2014 Feb;102 185-191. doi:10.1016/j.carbpol.2013.11.022. PMID: 24507271.
  • Kim EK, Tang Y, Kim YS, Hwang JW, Choi EJ, Lee JH, Lee SH, Jeon YJ, Park PJ. First evidence that Ecklonia cava-derived dieckol attenuates MCF-7 human breast carcinoma cell migration. Mar Drugs. 2015 Mar 30;13(4):1785-97. doi: 10.3390/md13041785. PubMed PMID: 25830682; PubMed Central PMCID: PMC4413187.
  • Kim EK, Tang Y, Kim YS, Hwang JW, Choi EJ, Lee JH, Lee SH, Jeon YJ, Park PJ. First evidence that Ecklonia cava-derived dieckol attenuates MCF-7 human breast carcinoma cell migration. Mar Drugs. 2015 Apr;13(4) 1785-1797. doi:10.3390/md13041785. PMID: 25830682; PMCID: PMC4413187.
  • Kim H, Kong CS, Lee JI, Kim H, Baek S, Seo Y. Evaluation of inhibitory effect of phlorotannins from Ecklonia cava on triglyceride accumulation in adipocyte. J Agric Food Chem. 2013 Sep 11;61(36):8541-7. doi: 10.1021/jf401454m. Epub 2013 Aug 30. PubMed PMID: 23957842.
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  • Kim HK. Ecklonia cava Inhibits Glucose Absorption and Stimulates Insulin Secretion in Streptozotocin-Induced Diabetic Mice. Evid Based Complement Alternat Med. 2012;2012:439294. doi: 10.1155/2012/439294. Epub 2012 May 8. PubMed PMID: 22645628; PubMed Central PMCID: PMC3356976.
  • Kim HK. Ecklonia cava Inhibits Glucose Absorption and Stimulates Insulin Secretion in Streptozotocin-Induced Diabetic Mice. Evid Based Complement Alternat Med. 2012;2012 439294. doi:10.1155/2012/439294. PMID: 22645628; PMCID: PMC3356976.
  • Kim J, Yoon M, Yang H, Jo J, Han D, Jeon YJ, Cho S. Enrichment and purification of marine polyphenol phlorotannins using macroporous adsorption resins. Food Chem. 2014 Nov 1;162:135-42. doi: 10.1016/j.foodchem.2014.04.035. Epub 2014 Apr 18. PubMed PMID: 24874368.
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  • Kim JG, Lim DW, Cho S, Han D, Kim YT. The edible brown seaweed Ecklonia cava reduces hypersensitivity in postoperative and neuropathic pain models in rats. Molecules. 2014 Jun 10;19(6):7669-78. doi: 10.3390/molecules19067669. PubMed PMID: 24918539.
  • Kim JG, Lim DW, Cho S, Han D, Kim YT. The edible brown seaweed Ecklonia cava reduces hypersensitivity in postoperative and neuropathic pain models in rats. Molecules. 2014;19(6) 7669-7678. doi:10.3390/molecules19067669. PMID: 24918539.
  • Kim JH, Lee NS, Jeong YG, Lee JH, Kim EJ, Han SY. Protective efficacy of an Ecklonia cava extract used to treat transient focal ischemia of the rat brain. Anat Cell Biol. 2012 Jun;45(2):103-13. doi: 10.5115/acb.2012.45.2.103. Epub 2012 Jun 30. PubMed PMID: 22822465; PubMed Central PMCID: PMC3398172.
  • Kim JH, Lee NS, Jeong YG, Lee JH, Kim EJ, Han SY. Protective efficacy of an Ecklonia cava extract used to treat transient focal ischemia of the rat brain. Anat Cell Biol. 2012 Jun;45(2) 103-113. doi:10.5115/acb.2012.45.2.103. PMID: 22822465; PMCID: PMC3398172.
  • Kim JY, Park SH, Seo GY, Kim YJ, Oh DC. Winogradskyella eckloniae sp. nov., a marine bacterium isolated from a brown alga Ecklonia cava. Int J Syst Evol Microbiol. 2015 May 15. pii: ijs.0.000334. doi: 10.1099/ijs.0.000334. [Epub ahead of print] PubMed PMID: 25979633.
  • Kim JY, Park SH, Seo GY, Kim YJ, Oh DC. Winogradskyella eckloniae sp. nov., a marine bacterium isolated from a brown alga Ecklonia cava. Int J Syst Evol Microbiol. 2015 May . doi:10.1099/ijs.0.000334. PMID: 25979633.
  • Kim KC, Kang KA, Zhang R, Piao MJ, Kim GY, Kang MY, Lee SJ, Lee NH, Surh YJ, Hyun JW. Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt. Int J Biochem Cell Biol. 2010 Feb;42(2):297-305. doi: 10.1016/j.biocel.2009.11.009. Epub 2009 Nov 18. PubMed PMID: 19931411.
  • Kim KC, Kang KA, Zhang R, Piao MJ, Kim GY, Kang MY, Lee SJ, Lee NH, Surh YJ, Hyun JW. Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt. Int J Biochem Cell Biol. 2010 Feb;42(2) 297-305. doi:10.1016/j.biocel.2009.11.009. PMID: 19931411.
  • Kim KC, Lee IK, Kang KA, Piao MJ, Ryu MJ, Kim JM, Lee NH, Hyun JW. Triphlorethol-A from Ecklonia cava up-regulates the oxidant sensitive 8-oxoguanine DNA glycosylase 1. Mar Drugs. 2014 Oct 28;12(11):5357-71. doi: 10.3390/md12115357. PubMed PMID: 25353254; PubMed Central PMCID: PMC4245535.
  • Kim KC, Lee IK, Kang KA, Piao MJ, Ryu MJ, Kim JM, Lee NH, Hyun JW. Triphlorethol-A from Ecklonia cava up-regulates the oxidant sensitive 8-oxoguanine DNA glycosylase 1. Mar Drugs. 2014 Nov;12(11) 5357-5371. doi:10.3390/md12115357. PMID: 25353254; PMCID: PMC4245535.
  • Kim KC, Piao MJ, Zheng J, Yao CW, Cha JW, Kumara MH, Han X, Kang HK, Lee NH, Hyun JW. Fucodiphlorethol G Purified from Ecklonia cava Suppresses Ultraviolet B Radiation-Induced Oxidative Stress and Cellular Damage. Biomol Ther (Seoul). 2014 Jul;22(4):301-7. doi: 10.4062/biomolther.2014.044. PubMed PMID: 25143808; PubMed Central PMCID: PMC4131532.
  • Kim KC, Piao MJ, Zheng J, Yao CW, Cha JW, Kumara MH, Han X, Kang HK, Lee NH, Hyun JW. Fucodiphlorethol G Purified from Ecklonia cava Suppresses Ultraviolet B Radiation-Induced Oxidative Stress and Cellular Damage. Biomol Ther (Seoul). 2014 Jul;22(4) 301-307. doi:10.4062/biomolther.2014.044. PMID: 25143808; PMCID: PMC4131532.
  • Kim M, Kim G. Electrospun PCL/phlorotannin nanofibres for tissue engineering: physical properties and cellular activities. Carbohydr Polym. 2012 Sep 1;90(1):592-601. doi: 10.1016/j.carbpol.2012.05.082. Epub 2012 May 30. PubMed PMID: 24751081.
  • Kim M, Kim G. Electrospun PCL/phlorotannin nanofibres for tissue engineering: physical properties and cellular activities. Carbohydr Polym. 2012 Sep;90(1) 592-601. doi:10.1016/j.carbpol.2012.05.082. PMID: 24751081.
  • Kim MJ, Kim HK. Insulinotrophic and hypolipidemic effects of Ecklonia cava in streptozotocin-induced diabetic mice. Asian Pac J Trop Med. 2012 May;5(5):374-9. doi: 10.1016/S1995-7645(12)60062-5. PubMed PMID: 22546654.
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  • Kim MM, Ta QV, Mendis E, Rajapakse N, Jung WK, Byun HG, Jeon YJ, Kim SK. Phlorotannins in Ecklonia cava extract inhibit matrix metalloproteinase activity. Life Sci. 2006 Sep 5;79(15):1436-43. Epub 2006 May 7. PubMed PMID: 16737716.
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  • Kim SK, Kong CS. Anti-adipogenic effect of dioxinodehydroeckol via AMPK activation in 3T3-L1 adipocytes. Chem Biol Interact. 2010 Jun 7;186(1):24-9. doi: 10.1016/j.cbi.2010.04.003. Epub 2010 Apr 10. PubMed PMID: 20385110.
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